Choosing the right audio interface with MIDI ports can make a small studio feel much more capable. The best models balance clean preamps, low-latency monitoring, useful I/O, and dependable MIDI connectivity.
Below, we focus on practical options for singers, guitarists, producers, streamers, and home-recording users who want a setup that is easy to grow into.
Best 10 Audio Interface with Midi Ports Picks for 2026
Pro Studio Hub
Focusrite Scarlett 4i4 4th Gen USB-C Audio Interface
- MIDI I/O plus 4-in/4-out layout
- Two mic preamps and two Hi-Z inputs
- Auto Gain, Clip Safe, and Air mode
Best For: recordists needing flexible I/O and MIDI support
Clean Two-Channel Pick
- 2-in/2-out interface with two preamps
- Hardware monitoring for easy tracking
- 24-bit/192kHz support in a compact build
Best For: simple recording setups that do not need MIDI
Portable Value Choice
Alloy Red 2x2 USB-C Audio Interface
- Class-compliant USB-C with no drivers
- Two combo inputs with phantom power
- Direct monitoring plus 24-bit/192kHz audio
Best For: portable recording and plug-and-play use
Budget MIDI Starter
PreSonus AudioBox 96 25th Anniversary USB Audio Interface
- Includes MIDI I/O for hardware control
- Two mic preamps and two instrument inputs
- Bus-powered and software bundled
Best For: beginners who want affordable MIDI-capable recording
Best Overall 4x4 MIDI Pick
- 4x4 USB audio/MIDI with 1x MIDI I/O
- 24-bit/192 kHz recording with four MIDAS preamps
- Metal chassis built for durability
Best For: Home studios needing multiple inputs and MIDI control
Best Budget Portable Pick
- Portable 2-channel USB interface
- 48 kHz audio with dual combo inputs
- No MIDI I/O, but easy direct monitoring
Best For: Beginners and streamers who need a simple USB interface
Best Compact MIDI Interface
- 2x2 USB interface with MIDI I/O
- 24-bit/192 kHz recording and bus power
- Two Onyx mic preamps with phantom power
Best For: Mobile musicians and small studios needing MIDI support
Top Studio Starter Pick
Focusrite Scarlett 2i2 4th Gen USB-C Audio Interface
- 120dB dynamic range and 24-bit/192kHz recording
- Auto Gain, Clip Safe, and Air mode simplify capture
- Includes major recording software and plugins
Best For: Beginners and home recordists who want clean mic and guitar recording
Best Compact Creator Interface
MAONO PS22 Lite USB Audio Interface
- 24-bit/192kHz recording with 106dB dynamic range
- XLR mic input with 48V phantom power and guitar input
- Compact design with direct monitoring and routing software
Best For: Podcasters, streamers, and beginners needing a compact vocal/guitar interface
Best Hybrid Workflow Pick
- Dual USB connectivity for computer and mobile use
- 70dB gain and -130dB EIN for clean mic capture
- Auto-Gain, loopback, and VST routing for creators
Best For: Creators who switch between computer, phone, and tablet recording
Pro Studio Hub – Focusrite Scarlett 4i4 4th Gen USB-C Audio Interface
If you want an audio interface with midi ports that can handle a growing setup, the Scarlett 4i4 4th Gen is built as a compact studio hub. It gives you two mic preamps, two Hi-Z inputs, four line inputs, four line outputs, and MIDI I/O, so it can cover vocals, guitars, synths, and drum machines in one box.
Best For: Musicians who need a flexible all-in-one interface for recording instruments, vocals, and MIDI gear.
Pros:
- Includes MIDI in/out alongside 4-in/4-out connectivity
- 120dB dynamic range and 24-bit/192kHz support
- Auto Gain and Clip Safe help protect takes
- Air mode adds presence and harmonic drive
Cons:
- More interface than you need if you only record one mic at a time
- Requires USB-C connectivity and included power supply for full setup
Overall, this is a strong pick if you want serious I/O and MIDI integration without stepping up to a much larger rig. It balances studio features with practical recording tools and bundled software.
Clean Two-Channel Pick – MOTU M2 USB-C Audio Interface
The MOTU M2 is a straightforward audio interface with midi ports not included, but it is a strong choice if your focus is simple, high-quality recording. With 2-in/2-out operation, two preamps, hardware monitoring, and 24-bit/192kHz support, it suits compact desktop setups.
Best For: Solo musicians and small setups that want clean sound and low-latency monitoring.
Pros:
- 2 preamps with 2-in/2-out USB-C connectivity
- Hardware monitoring for practical tracking
- 24-bit/192kHz recording support
- Compact, desktop-friendly design
Cons:
- No MIDI I/O for external synths or controllers
- Only two channels, so it is less flexible for larger sessions
If you do not need MIDI connections, the M2 keeps the workflow lean while still aiming for strong audio performance. It is best treated as a focused recording interface rather than a studio expansion hub.
Portable Value Choice – Alloy Red 2×2 USB-C Audio Interface
This 2×2 audio interface is aimed at creators who want an easy, portable way to record vocals or instruments. It offers class-compliant USB-C connectivity, two combo jacks, 24-bit/192kHz conversion, and direct monitoring in a one-cable setup.
Best For: Mobile recordists and home studio users who want a simple plug-and-play interface.
Pros:
- Plug-and-play USB-C design with no drivers required
- Two combo inputs with 48V phantom power
- 24-bit/192kHz fidelity for detailed recording
- Direct monitoring and 3.5mm headphone connection
Cons:
- No MIDI ports for external gear
- Only 2-channel input/output limits expansion
For creators who value portability and simplicity, this interface covers the essentials without adding setup hassle. It is a practical choice if your priority is quick, clean recording rather than larger studio connectivity.
Budget MIDI Starter – PreSonus AudioBox 96 25th Anniversary USB Audio Interface
If you need an audio interface with midi ports on a budget, the AudioBox 96 is a practical entry point. It combines two Class-A mic preamps, two instrument inputs, MIDI I/O, and bus-powered USB 2.0 operation for portable recording and simple studio setups.
Best For: Beginners and budget-conscious musicians who want MIDI support plus basic recording flexibility.
Pros:
- MIDI I/O included for MIDI hardware
- Two Class-A mic preamps and two instrument inputs
- Bus-powered USB 2.0 design for mobile use
- Includes Studio One Artist and Studio Magic Plug-In Suite
Cons:
- 24-bit/96kHz max sample rate is lower than some rivals
- Feature set is more basic than higher-end multi-I/O interfaces
Overall, the AudioBox 96 delivers the essentials for recording and MIDI integration without stretching the budget. It is especially appealing if you want a small, reliable interface with included software to get started quickly.
Best Overall 4×4 MIDI Pick – Behringer U-PHORIA UMC404HD
If you want an audio interface with midi ports that can handle recording, playback, and hardware control in one box, the Behringer U-PHORIA UMC404HD is a strong all-around pick. It offers 4×4 USB audio/MIDI, 24-bit/192 kHz resolution, and four MIDAS-designed mic preamps for a more capable home studio setup.
Best For: Home studios that need multiple inputs, MIDI I/O, and high-resolution recording.
Pros:
- 4×4 USB 2.0 audio/MIDI interface with 1x MIDI I/O
- 24-bit/192 kHz resolution for professional audio quality
- Four MIDAS-designed mic preamps with +48V phantom power
- Metal chassis built for durability
Cons:
- Larger and heavier than compact 2-channel interfaces
- May be more interface than you need for simple podcast setups
Overall, the UMC404HD makes sense when you need a rugged interface with MIDI ports and enough I/O to grow into. Its feature set is broad, and the included compatibility with major recording software makes it easy to fit into a typical studio workflow.
Best Budget Portable Pick – M-AUDIO M-Track Duo
The M-AUDIO M-Track Duo is a simple, portable choice if you do not need an audio interface with midi ports but want a straightforward two-channel setup for recording, podcasting, or live streaming. It delivers 48 kHz audio resolution, dual combo inputs, and direct monitoring for low-latency tracking.
Best For: Beginners, streamers, and podcasters who want a compact USB interface without MIDI features.
Pros:
- Portable USB interface with 48 kHz audio resolution
- Two combo XLR/Line/Instrument inputs with phantom power
- Zero-latency monitoring with USB/Direct switch
- Includes MPC Beats software
Cons:
- No MIDI I/O, so it is not the right fit for MIDI gear
- Only two channels, which limits expansion
If your priority is a compact interface for vocals, guitar, or streaming, the M-Track Duo covers the basics well. It is not aimed at users who need MIDI ports, but it is a practical entry-level option for simple recording setups.
Best Compact MIDI Interface – Mackie Onyx Producer 2X2
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonIf you are shopping for an audio interface with midi ports in a compact format, the Mackie Onyx Producer 2X2 is built for small studios and mobile recording. It combines 24-bit/192 kHz recording, MIDI I/O, two Onyx mic preamps, and bus-powered USB 2.0 operation.
Best For: Mobile musicians and small studios that want MIDI support in a durable 2×2 interface.
Pros:
- 2×2 USB interface with MIDI I/O
- 24-bit/192 kHz recording support
- Two Onyx mic preamps with 48V phantom power
- Bus-powered, with zero-latency direct monitoring
Cons:
- Only two inputs and two outputs
- Limited channel count compared with larger studio interfaces
The Onyx Producer 2X2 is a focused option when you want solid audio quality plus MIDI in a travel-friendly unit. Its small footprint and bus-powered design make it especially convenient for recording on the go.
Top Studio Starter Pick – Focusrite Scarlett 2i2 4th Gen USB-C Audio Interface
If you want an audio interface with midi ports, the Scarlett 2i2 4th Gen is not that kind of unit—but it is a strong two-channel USB-C interface for vocals and guitars. It focuses on clean conversion, simple recording, and useful safeguards like Auto Gain and Clip Safe, making it easy to get polished results fast.
Best For: Beginners and home recordists who want straightforward, high-quality mic and guitar recording.
Pros:
- 120dB dynamic range and 24-bit/192kHz support for detailed recording
- Auto Gain helps set levels quickly, while Clip Safe helps prevent distortion
- Air mode adds presence and harmonic richness to vocals and guitars
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion
Cons:
- No MIDI ports, so it will not suit keyboard or controller users who need DIN MIDI
- Only two input channels, which limits larger recording setups
- Best suited to simple mic-and-guitar workflows rather than expanded routing
This is a solid pick if your priority is easy, studio-quality recording rather than extra connectivity. It keeps the workflow simple and adds helpful tools that reduce setup mistakes.
Best Compact Creator Interface – MAONO PS22 Lite USB Audio Interface
If you are comparing an audio interface with midi ports, the MAONO PS22 Lite is aimed more at creators than MIDI-based musicians. It is a compact USB interface built for vocals, guitar, and streaming, with 24-bit/192kHz capture, direct monitoring, and routing tools that make day-to-day recording simple.
Best For: Podcasters, streamers, and beginners who want a small, easy-to-use interface for vocals and guitar.
Pros:
- 24-bit/192kHz recording with 106dB dynamic range
- XLR mic input supports condenser and dynamic mics with up to 56dB preamp and 48V phantom power
- Dedicated instrument input for guitar, plus direct monitoring for easier tracking
- ProStudio Routing Software adds loopback and low-latency ASIO support
Cons:
- No MIDI ports, so it is not designed for external MIDI gear
- Best for smaller setups rather than more advanced multi-device studios
- Routing features may be more than a casual user needs
The PS22 Lite stands out for its compact size and creator-friendly workflow. If you want simple recording and streaming features without extra hardware complexity, it is an easy fit.
Best Hybrid Workflow Pick – MAONO P1 USB Audio Interface
For buyers searching for an audio interface with midi ports, the MAONO P1 is better described as a hybrid USB interface for modern content workflows. It connects to computer and mobile devices, supports 24-bit/192kHz recording, and adds routing tools that are useful for creators who switch between music, streaming, and social content.
Best For: Creators who want one interface for computer, phone, and tablet recording workflows.
Pros:
- Dual USB ports with MFi-certified connectivity for computer and mobile devices
- Up to 70dB gain and -130dB EIN for strong dynamic mic performance
- Auto-Gain, mute controls, and stream mode help simplify live use
- ProStudio2 adds loopback, routing, and VST effect support
Cons:
- No MIDI ports listed, so it does not cover MIDI controller connectivity
- Advanced routing features may be more than a basic user needs
- Designed around creator workflows rather than traditional studio expansion
The P1 is the most flexible option here if your setup moves between a computer and mobile devices. It is especially appealing for creators who want strong mic gain, easy routing, and fast switching between tasks.
How We Picked the Best Audio Interface with Midi Ports
We looked for interfaces that deliver reliable sound quality, stable drivers, and the kind of connectivity most buyers actually use day to day. Priority went to units with solid MIDI support, at least one flexible input path, straightforward monitoring, and strong value for the price.
We also considered build quality, portability, gain range, and whether each model fits a beginner desk setup or a more ambitious home studio.
Quick Comparison
Some models are better for simple two-channel recording and streaming, while others are designed for expanded routing or extra inputs. If you mainly track vocals and guitar, a compact 2-in/2-out unit may be enough. If you want drums, synths, or external controllers in the same system, a 4×4 or similarly expanded interface gives you more room to grow.
Key Buying Factors for an Audio Interface with Midi Ports
Input and Output Count
Match the interface to your workflow. Solo artists can usually get by with one or two inputs, but creators recording multiple instruments or hardware synths may need more line inputs and outputs.
MIDI Connectivity
Confirm whether the MIDI ports are standard 5-pin DIN connections and whether you need both input and output. This matters if you plan to control synths, drum machines, or external sequencers.
Preamps and Gain
Clean preamps and enough gain are important for dynamic microphones and low-output instruments. If you use gain-hungry mics, look for interfaces known for a stronger boost range and low noise.
Monitoring and Latency
Direct monitoring, clear level controls, and stable low-latency performance can improve recording sessions more than extra features you may never use.
Platform Compatibility
Check support for your computer or mobile device, especially if you record on Mac, Windows, iPad, or phone. An Audio Interface with Midi Ports should fit your ecosystem without extra workarounds.
Who Should Buy Which Audio Interface with Midi Ports?
Choose a compact 2-channel interface if you record vocals, guitar, or podcasts and want a simple setup. Pick a more feature-rich 4×4 unit if you use hardware MIDI gear, need extra I/O, or want more routing flexibility.
If you are upgrading from a basic starter interface, focus on the features you will actually use most: mic gain, monitoring, and MIDI connectivity. That combination usually matters more than headline specs alone.